5-amino-4-carbamoyl imidazole nucleoside (AICAR) can also be used as raw materials for the synthesis of 2-mercaptoinosine and isoproterenoinosine. As feed additives, 2-mercaptoinosine and isoproterenoinosine can enhance animal immunity, and the dosage is increasing at present; However, the current 5-amino-4-carbamoyl imidazole nucleoside (AICAR) is produced by chemical synthesis of various organic materials. This method has the disadvantages of high cost, large environmental pollution and difficult treatment of pollutants.

      The present invention provides a 5- amino-4-carbamoyl-imidazol-nucleoside producing strain and production of 5- amino-4-carbamoyl-imidazol-nucleosides（AICAR）, microbial strains are provided by the selection of Bacillus subtilis XG15 CCTCC M 205040. The strain with the fermentation strains using sugar feedstocks for fermentation, fermentation 50-80 hours, and can produce 5- amino-4-carbamoyl